The work aims to establish the method for the determination of migration levels of 9 volatile methylsiloxanes (VMSs) in the food simulants from the infant food-contact silicone teats. Distilled water, acetic acid (volume fraction: 3%) and ethanol (volume fraction: 50%) were used as food simulants. Purge and trap coupled with gas chromatography-mass spectrometry (P&T-GC-MS) was used to determine the migration levels of 9 VMSs in silicone teats after soaked for 24 h at 40 ℃. The result of methodology evaluation showed that the method of high sensitivity, high recovery rate and good selectivity could meet the requirements of actual determination. The result of migration experiments indicated that 9 VMSs were all detected. The total migration level of VMSs in ethanol (50%) from three brands of silicone teats was the highest, which ranged from 2.62~11.58 μg/mL. There is certain risk of migration and ingestion of VMSs from silicone teats during the use, and the risk is higher in high-fat foods.