The work aims to clarify the game relationship and dynamic evolution process of each subject in reducing the sources of packaging garbage, and put forward relevant countermeasures and suggestions to reduce the source of packaging garbage. The evolutionary game theory was used to analyze the evolution process of government, enterprises and consumers in the source reduction of packaging garbage. Six groups of representative data were selected for the simulation by Matlab software. The research results showed that, in the initial stage of reducing the source of packaging garbage, the government guidance played a significant leading role. The parties could not be made to take the strategy of participation only by moderately improving the subsidies for the packaging enterprises. Therefore, it was necessary to increase the penalty for over-packaged enterprises. Consumers' awareness of environmental protection had a great impact on the equilibrium results of the system. Enterprises should adjust their own packaging strategies so as to increase economic benefits from assuming social responsibilities. Based on the study of the evolution characteristics of the decision-making behavior of multiple stakeholders in the management of the source reduction of packaging garbage, the countermeasures and suggestions for the source reduction of packaging garbage are put forward.