The work aims to develop a detection method that can measure the migration of acrylamide and 6 aromatic amines. A solid phase extraction-high performance liquid chromatography (HPLC) was established to measure the migration of acrylamide and 6 aromatic amines, through screening the types of columns based on solid-phase extraction, and optimizing the purification method and liquid chromatography conditions. The acrylamide had a good linear relation (R2=0.9989), the detection wavelength was 220 nm and the limit of detection was 0.01 mg/L when the concentration range was 0.2~20 mg/L. The aromatic amine had a good linear relation (R2＞0.998), the detection wavelength was 220 and 280 nm and the limit of detection was also 0.01 mg/L when the concentration range was 0.2~20 mg/L. In the water sample, the recovery of each compound was above 90% while the relative standard deviation (RSD) was 2.3%~5.9%. In the practical samples, the recoveries of aromatic amines were above 86.9% with 2.0%~6.1% of RSD, while the recovery of acrylamide was 78.7%~81.9% with 4.2%~6.2% of RSD. Featured by simple processing step, good separation effect and high precision, the method is worth being popularized as a routine detection method from the viewpoint of improving detection efficiency and saving cost.