The work aims to make consumers distinguish the authenticity and the quality of drugs by anti-counterfeiting identifications commonly used on drug package and to understand the application of intelligent anti-counterfeiting technology in drug package. Anti-counterfeiting identification commonly used on drug package was introduced, and the application of intelligent anti-counterfeiting technology in anti-counterfeiting package at home and abroad was summarized combined with examples and pictures of anti-counterfeiting package of drugs. Anti-counterfeiting package of drugs will become a favorable safeguard for some drugs manufacturers, especially some famous drugs manufacturers, to prevent illegal elements from counterfeiting their products. The design of anti-counterfeiting package of drugs is not only convenient for consumers to identify the authenticity of drugs, but also plays a vital role in enhancing the brand image of drug companies.