The work aims to solve the problem of vibration and noise caused by intermittent motion, improve the accuracy and reliability of synchronous belt transmission and study the effect of intermittent motion on the high-speed synchronous belt transmission device. By studying a pair of meshing contact problems between belt teeth and gear teeth, the vibration balance equation between adjacent fixtures on the lower belt of periodic load excitation was established. Then, under the guidance of theoretical model, Recurdyn software was used to establish the dynamic simulation model of high-speed synchronous belt intermittent transfer system. The factors affecting the system position accuracy and dynamic performance were analyzed. The data obtained indicated that the lateral and longitudinal vibrations of the synchronous belt were caused by the viscoelasticity of the tape elements, and the positioning accuracy in the middle of the tape was low. According to the effect of intermittent motion on the dynamic performance of high-speed synchronous belt intermittent transmission device, it is possible to increase the reliability of the synchronous belt transmission by an additional tensioner with a mid-section or a stitch-free synchronous belt with steel wire in the middle.