The work aims to study the cushioning packaging structure and cushioning effect of egg. The designed cushioning packaging structure carried out the angle drop simulation at the drop height of 0.6 m with the Ansys/LS-DYNA finite element analysis software to obtain the equivalent stress nephogram of the egg and package in contact with the ground, at the time of springback and at the end of drop, and the acceleration curve of the dangerous points, to simulate the egg stress change in the course of circulation of the egg when the package was subject to shock and vibration, so as to verify the cushioning effect of the cushioning packaging. The maximum equivalent stress of the contact between the package and the ground was 0.784 MPa, lower than the limit stress of the corrugated paperboard; the maximum acceleration of the dangerous point was 59g, smaller than the crisp value 60g of the egg in the process of dropping. Designed cushioning packaging can give good cushioning effect and effectively improve the safety of egg transport process.