The work aims to study the effect of impact velocity and strain rate on the in-plane cushioning properties of hexagonal honeycomb by changing the thickness in the compression direction, namely, the number of honeycomb layers. Software Ansys/LS-DYNA was used to simulate the effect of impact velocity on the in-plane cushioning properties of honeycomb under constant strain rate, and the effect of strain rate on the in-plane cushioning properties of honeycomb under constant velocity value. Three sets of strain rate constants (300, 500, 1,000 s−1) were set to study the effects of different impact velocities on the dynamic peak stress of the honeycomb. The dynamic peak stress increased with the increase of the velocity. Three sets of strain rate constants (3, 50, 100 m/s) were set to study the effects of different strain rates on the dynamic peak stress of the honeycomb. The dynamic peak stress remained basically unchanged with the increase of strain rate. When the tested material is bilinear hardened aluminum substrate, and the wall material is not sensitive to the strain rate, the strain rate basically has no influence on the dynamic mechanical property and cushioning property of the regular hexagonal honeycomb.