目的 探索纸质食品、药品包装与纸基微流控检测芯片的整合方法与规律。方法 在传统纸质食品或药品包装的内表面，通过喷蜡打印的方法，整合具有特定生物化学检测作用的纸基微流控芯片，并探索微流体在包装内表面构成的纸基微流控芯片中的运用规律。结果 通过喷蜡打印，成功地将纸基微流控芯片整合在了传统纸质食药包装的内表面，经过测试可以完成液体pH检测等基础生物化学检测应用。结论 将纸基微流控芯片与食药纸质包装相结合，为食品、药品的实时和现场自我检测提供了新的思路和手段，该方法不仅成本低廉、易于操作，且检测精度高。

To study integration methods and rules of paper-based microfluidic detection chips and the paper packaging of food and medicine. The paper-based microfluidic chips of typical biochemistry features were integrated by printing on the inner side of the packaging with a commercial wax printer. And the application rules of microfluid in paper-based microfluidic chips composed on the inner packing surface were explored. The wax praying printing integrated the paper-based microfluidic chips on the inner surface of traditional food and medicine packaging successfully. Basic chemical/biological test and application such as pH test of liquid could be completed by test. The integration of paper-based microfluidics and paper packaging of food/medicine provide a novel approach for the real time and in-situ self inspection of food quality or drug efficacy. It is featured with low cost, easy operation and high test precision.