It aims to research the application and integration of visual illusion art in graphic advertisement. It summarizes the artistic features of visual illusion from the angle of shape and color respectively. The practical significance and value of applying the visual illusion in graphic advertising are also discussed. It points out that by utilizing visual function and visual psychology properly and choosing the appropriate corresponding visual illusion pattern based on the advertisement contents aiming to convey, it could create a magical and plentiful visual effect and arouse people's strong watching interest so as to achieve the purpose of having a favorable visual information transmission.