目的 制备一种以壳聚糖为主要成分的抗菌薄膜，并研究其性能。方法 壳聚糖、聚乙烯醇(PVA)、纳米二氧化钛和甘油等通过流延法制成膜，将壳聚糖与聚乙烯醇的质量比、纳米二氧化钛用量、甘油用量以及干燥温度等4个因素作为试验因素，通过正交试验，以抗菌性、水溶性和力学性能作为指标，对其性能进行评价。结果 当壳聚糖与PVA质量比为8∶2，纳米TiO2质量分数为0.75%，甘油质量分数为0.5%，干燥温度为70 ℃时，抗菌复合膜的综合性能最好。结论 加入聚乙烯醇和纳米二氧化钛并以壳聚糖为主要成分的抗菌薄膜具有较好的抗菌性、水溶性和力学性能，且具有抗菌缓释性。

The work aims to research the process to prepare antibacterial film mainly composed of chitosan and its performance. The antibacterial film was produced by chitosan, polyvinyl alcohol (PVA), nano titanium dioxide (nano-TiO2) and glycerin with tape casting technique. With four factors as experimental factors, including the mass ratio of chitosan and PVA, the amount of nano titanium dioxide and glycerin dosage and the drying temperature, based on the orthogonal experiment, the performance of the film was evaluated, with antimicrobial property, water solubility and mechanical property as the indicators. When the mass ratio of chitosan and PVA was 8∶2, the mass fractions of nano- TiO2 and glycerol were respectively 0.75% and 0.5%, and the drying temperature was 70℃, the antibacterial composite film had the best comprehensive performance. The antibacterial film added with PVA and nano-TiO2 and mainly composed of chitosan has better antimicrobial property, water solubility and mechanical property, and it also has antimicrobial slow-release property.