目的 对水溶性聚氨酯胶黏剂的制备工艺进行优化，以提高胶黏剂的粘度。方法 采用响应面分析法优化水溶性聚氨酯胶黏剂制备工艺，研究预聚体、改性剂和增韧剂质量分数及其交互作用对胶黏剂粘度的影响，找出最佳配比工艺。结果 在预聚物、改性剂、增韧剂的质量分数分别为47.24%，6.24%，5.84%，且余量为溶剂的条件下，水溶性聚氨酯胶黏剂的粘度理论预测值为2716.64 mPa•s，实测值为2658.32 mPa•s。结论 响应面法可以用于优化水溶性聚氨酯胶黏剂的制备工艺。

This research aims to improve viscosity of waterborne polyurethane adhesive by the optimal preparation technology. Response surface analysis was applied to gain the optimal preparation technology of waterborne polyurethane adhesive. Effect on viscosity of waterborne polyurethane adhesive of the prepolymer, modifier, flexibilizer concentration and the interactions were studied to gain the optimal preparation technology. The results showed that the theoretical predictions (2716.64 mPa•s) agreed well with the experimental results (2658.32 mPa•s) when there were 47.24% (mass percent) prepolymer, 6.24% (mass percent) modifier, 5.84% (mass percent) flexibilizer, and 40.68% (mass percent) solvent. Response surface analysis can be used for optimization preparation technology of waterborne polyurethane adhesive.