目的 将水性涂布纸作为食品接触用纸时，其安全风险未知，通过对水性涂层纸中半挥发性迁移物进行筛查和安全评估，探究水性涂布纸的潜在安全风险。方法 以体积分数为4%的乙酸、体积分数为50%的乙醇、体积分数为95%的乙醇和异辛烷为食品模拟物进行迁移试验，使用二氯甲烷液萃取迁移物，并通过气相色谱–质谱联用(GC-MS)法、MS-DIAL软件和NIST质谱库对半挥发性迁移物进行非靶向筛查和定量分析，结合特定迁移限量(SML)和毒理学关注阈值法(TTC)进行初步风险识别和评估。结果 初步识别出21种半挥发性迁移物，主要与造纸纤维原料、乳液助剂等有关，比如长叶烯、脱氢枞酸甲酯等，包括7种Cramer Ⅲ类毒性物质、1种Cramer Ⅱ类物质。少数具有SML的物质(比如邻苯二甲酸二丁酯、邻苯二甲酸二辛酯)在体积分数为95%的乙醇迁移中的最高浓度均处于安全范围，Cramer Ⅲ类油酸酰胺、秋水仙胺的迁移量超出了安全摄入暴露阈值(0.09 mg.kg⁻¹.d⁻¹)，存在一定安全隐患。在其他条件下，迁移物的浓度均低于相应的Cramer安全阈值。结论 水性涂布纸在长时间接触酒精性食品的情况下，更多的风险物质会迁移到食品中，存在潜在的安全问题。

The work aims to explore the potential safety risks of water-borne coated paper through screening and safety assessment of semi-volatile migrants in water-borne coated paper. Specific migration tests with 4% acetic acid, 50% ethanol, 95% ethanol and isooctane as food simulants were conducted. Migrants were extracted with methylene chloride solution. Non-targeted screening and quantitative analysis of semi-volatile migrants were performed by gas chromatograph-mass spectrometry (GC-MS), MS-DIAL software and NIST mass spectrometry library, and preliminary risk identification and assessment were performed in combination with specific migration limit (SML) and toxicological threshold of concern (TTC). There were 21 tentatively identified migrants, mainly related to paper raw materials and emulsion additives, such as longifolene, and methyl dehydroabietate, including 7 Cramer Ⅲ substances and 1 Cramer Ⅱ substance. For a small number of substances with SML (e.g., dibutyl phthalate, dioctyl phthalate), the maximum concentration of migrants in 95% ethanol was in the safe range. While the migration of Cramer Ⅲ oleamide and colchicine exceeded the safe threshold of daily intake, posing the potential human risk. In all other conditions, the concentrations of the migrants were below the corresponding Cramer safe threshold. The conclusion of the research is that in the case of prolonged exposure to alcoholic food, more risk substances will be exposed and migrated to the food product, causing potential safety problems.