目的 综述PET包装材料中聚酯低聚物的研究现状，包括筛查识别、迁移检测、风险评估及政策法规。方法 PET包装材料中聚酯低聚物的筛查识别主要采用液相色谱-高分辨率质谱技术进行，结合靶向筛查和非靶向筛查手段。聚酯低聚物的迁移检测主要是测定不同条件聚酯低聚物从PET包装材料向食品模拟物的迁移。结果 部分研究开展了真实食品中低聚物的含量测定，并采用合适的方法对食品样品进行前处理。聚酯低聚物的风险评估通常是将食品/食品模拟物中的迁移量和法规中的迁移限量进行比较。对法规中未列出的低聚物，通常采用毒理学关注阈值(TTC)方法结合Cramer决策树进行风险评估。由于实验数据的缺乏，针对PET内聚酯低聚物的法规还十分有限。结论 随着PET包装材料的广泛使用，特别是新型PET包装材料的出现，有必要对PET中聚酯低聚物的潜在风险进行深入研究，以确保食品安全。应注重高分辨率质谱在聚酯低聚物筛查及迁移检测中发挥的作用，为后续风险评估提供重要数据支持。

The work aims to review the current research progress of oligomers in PET packaging materials, including identification, migration detection, risk assessment, policies and regulations. Identification of oligomers in PET packaging materials was mainly conducted by liquid chromatography coupled to high resolution mass spectrometry (HRMS) with both targeted and non-targeted screening procedures. Migration detection of oligomers was carried out by measuring the amount of oligomers migrating from PET packaging materials to food simulants under different conditions. Detection of oligomers in real foods was also conducted, while appropriate sample pretreatment methods were applied. Risk assessment of oligomers was mainly performed by comparing the concentration of oligomers in food/food simulants with the corresponding migration limits either listed in policies and regulations or obtained via a threshold of toxicological concern (TTC) approach with implementation of Cramer classification scheme. By far, due to the lack of experimental data, policies and regulations on oligomers in PET are scarce. With the expanding application of PET in packaging, especially the commercialization of novel PET materials, it is quite necessary to fully investigate the potential risks of oligomers in PET to ensure food safety. It is believed that HRMS plays an important role in exploring oligomers in PET and their migration behaviors, which in turn could provide essential data for future risk assessment.