目的 对国内外微纳加工技术在包装防伪中的应用研究进行梳理，帮助相关行业从业者更清晰、全面地了解当前微纳加工技术包装防伪领域的发展和应用现状，推动微纳加工技术在该领域的推广应用。方法 本文将相关研究大致分为微纳加工技术在新型防伪标签的制备、新型防伪材料制备和数字防伪领域的应用研究等3个方面，并对相关研究概况、关键科学技术实现方法以及核心防伪机理进行梳理，分析微纳加工技术应用于包装防伪中的优缺点和发展趋势，聚焦复合防伪技术的挑战和未来发展方向。结论 国内外研究综述表明，微纳加工技术的快速发展为防伪技术提供了一种全新的技术和方法，微纳加工技术与信息技术等构成的复合防伪技术更是表现出了巨大的商业化应用潜力。但目前微纳加工技术在包装防伪中的应用还处于初级阶段，大部分实验室成果在面临产业化落地时仍受到成本、可靠性等因素的限制。未来在如何满足精度要求的同时，进一步降低设备和材料成本，优化工艺流程，还需要进行更深入的探索研究。

The work aims to provide an overview of the research on the application of micro-nano processing technologies in packaging anti-counterfeiting to help practitioners in related industries to understand more clearly and comprehensively the current development and application status of micro-nano processing technologies in packaging anti-counterfeiting, and promote their promotion and application in this field. In this work, relevant research was divided into three aspects, namely, the application research of micro-nano processing technology in the preparation of new anti-counterfeit labels, the preparation of new anti-counterfeit materials and digital anti-counterfeiting field. Relevant research profiles, key scientific and technological implementation methods and core anti-counterfeiting mechanisms were sorted out. Advantages, disadvantages and the development trend of micro-nano processing technologies in packaging anti-counterfeiting were analyzed. Challenges and future development directions of composite anti-counterfeiting technologies were highlighted. This research shows that the rapid development of micro-nano processing technologies provides a new tool and technology for anti-counterfeiting technology. The composite anti-counterfeiting technology composed of micro-nano processing technology and information technology, etc. has shown great potential for commercial application. However, the application of micro-nano processing technologies in packaging anti-counterfeiting is still in the initial stage, and most of the laboratory results are still limited by cost and reliability when facing industrialization. How to further reduce the cost of equipment and materials and optimize the process flow while meeting the accuracy requirements in the future requires more in-depth exploration and research.